Kodi Family Mediterranean fever (FMF) ndi chiyani?

Familial Mediterranean Fever ndi matenda a autosomal recessive cholowa omwe amadziwonetsera okha ndi madandaulo a ululu wa mmimba ndi kutentha thupi pakuukira ndipo amatha kusokonezedwa ndi appendicitis pachimake.

Kodi Matenda a FMF (Familial Mediterranean Fever) ndi chiyani?

Family Mediterranean Fever imapezeka kawirikawiri mmayiko omwe ali mmalire a Mediterranean. Ndiwofala ku Turkey, North Africa, Armenians, Arabs ndi Ayuda. Nthawi zambiri imadziwika kuti Familial Mediterranean Fever (FMF).

Matenda a FMF amadziwika ndi kupweteka kwa mmimba, kupweteka ndi kupwetekedwa kwa nthiti (plevititis) ndi kupweteka kwa mafupa ndi kutupa (nyamakazi) chifukwa cha kutupa kwa mmimba, komwe kumabweranso kuukira ndipo kumatha masiku 3-4. Nthawi zina, kufiira kwa khungu kutsogolo kwa miyendo kungawonjezedwe pachithunzichi. Nthawi zambiri, madandaulowa amatha okha mkati mwa masiku 3-4, ngakhale palibe chithandizo choperekedwa. Kuukira mobwerezabwereza kumapangitsa kuti puloteni yotchedwa amyloid iwunjikane mthupi lathu pakapita nthawi. Amyloid nthawi zambiri imadziunjikira mu impso, komwe imatha kuyambitsa kulephera kwa impso. Pamlingo wocheperako, imatha kudziunjikira mmitsempha yamakoma ndikuyambitsa vasculitis.

Zotsatira zachipatala zimachitika chifukwa cha kusintha kwa jini yotchedwa pyrin. Amafalitsidwa mwachibadwa. Ngakhale kukhalapo kwa majini awiri odwala pamodzi kumayambitsa matendawa, kunyamula jini ya matenda sikumayambitsa matendawa. Anthu awa amatchedwa "onyamula".

Kodi Zizindikiro za Familial Mediterranean Fever (FMF) ndi ziti?

Familial Mediterranean Fever (FMF) ndi vuto la majini lomwe limapezeka kudera la Mediterranean. Zizindikiro za FMF zimatha kuwoneka ngati kukomoka, kupweteka kwambiri mmimba, kupweteka mmafupa, kupweteka pachifuwa, ndi kutsekula mmimba. Febrile khunyu imayamba mwadzidzidzi ndipo nthawi zambiri imatha kuyambira maola 12 mpaka 72, pomwe ululu wammimba umakhala wakuthwa, makamaka kuzungulira mchombo. Kupweteka kwapakati kumamveka makamaka mmagulu akuluakulu monga bondo ndi bondo, pamene kupweteka pachifuwa kumatha kuchitika kumanzere. Kutsekula mmimba kumawonekera pakapita nthawi ndipo kumamveka kwakanthawi kochepa.

Kodi Matenda a Familial Mediterranean Fever (FMF) amapezeka bwanji?

Kuzindikira kumapangidwa potengera zomwe zapezeka mchipatala, mbiri yabanja, zofufuza komanso mayeso a labotale. Mayeserowa, pamodzi ndi kukwera kwakukulu kwa leukocyte, kuwonjezeka kwa sedimentation, kukwera kwa CRP ndi kukwera kwa fibrinogen, kumathandizira kuzindikira kwa Familia Mediterranean Fever. Ubwino wa kuyezetsa majini kwa odwala ndi ochepa chifukwa masinthidwe omwe azindikirika mpaka pano angapezeke abwino mu 80% ya odwala a Familial Mediterranean Fever. Komabe, kusanthula kwa majini kungakhale kothandiza pazochitika za atypical.

Kodi ndizotheka kuchiza Matenda a Familial Mediterranean Fever (FMF)?

Zatsimikiziridwa kuti chithandizo cha colchicine cha Familial Mediterranean Fever chimalepheretsa kuukira komanso kukula kwa amyloidosis mwa odwala ambiri. Komabe, amyloidosis akadali vuto lalikulu kwa odwala omwe satsatira chithandizo kapena akuchedwa kuyamba colchicine. Chithandizo cha Colchicine chiyenera kukhala moyo wonse. Zimadziwika kuti chithandizo cha colchicine ndi chithandizo chotetezeka, choyenera komanso chofunikira kwa odwala omwe ali ndi matenda a Mediterranean fever. Ndibwino kuti mugwiritse ntchito ngakhale wodwalayo atakhala ndi pakati. Colchicine sichinawonetsedwe kuti ili ndi zotsatira zovulaza kwa mwanayo. Komabe, tikulimbikitsidwa kuti odwala omwe ali ndi pakati omwe ali ndi matenda ambanja la Mediterranean amakumana ndi amniocentesis ndikuwunika mawonekedwe a mwana wosabadwayo.